Ben Franklin Technology Partners of
Southeastern PA 2025 Impact Report
A letter from our
President and CEO
Scott Nissenbaum
As I reflect on 2025, I am reminded that innovation is ultimately about people—entrepreneurs with bold ideas, investors willing to take calculated risks, and partners committed to building a stronger regional economy. At Ben Franklin Technology Partners of Southeastern Pennsylvania, our role is to connect those people and provide the capital, expertise, and relationships that help innovative companies grow.
This past year, we provided $6.5 million in funding for 28 companies, helping entrepreneurs transform promising ideas into growing businesses. Across our portfolio of 188 active companies, these investments supported the creation of 259 new jobs, the retention of more than 2,000 positions, and leveraged more than $521 million in additional capital. We also remained committed to expanding opportunity, with almost half of our portfolio led by BIPOC founders and nearly half led by women. These outcomes demonstrate that innovation and inclusion are essential to long-term economic growth for our region.
Greater Philadelphia also reached an important milestone this year, rising to the No. 5 biopharma cluster in the United States. This recognition reflects the strength of our regional innovation ecosystem, and Ben Franklin is proud to support the entrepreneurs and companies driving that momentum across life sciences, technology, manufacturing, and other emerging industries.
This year also marked an exciting milestone for Ben Franklin Technology Partners as we relocated our headquarters to Center City Philadelphia. More than a change of address, our new location places us closer to entrepreneurs, investors, universities, and partners while creating new opportunities for collaboration and community engagement. It reflects our commitment to serving as a hub for innovation throughout Southeastern Pennsylvania.
Thank you to our founders, portfolio companies, investors, board members, staff, and partners for making this work possible. Together, we are strengthening our region's innovation economy and creating opportunities that will benefit future generations. We look forward to building on this momentum in the year ahead.
Scott Nissenbaum
President and CEO
Measuring Ben Franklin's
Impact in 2025
Ben Franklin Approved
Million
Accross Southeastern PA
Companies
Investment By Sector
Tech
Million
Companies
Healthcare
Million
Companies
Total Portfolio
Jobs Created / Retained
Dollars Leveraged By Portfolio
Social Impact
BiPOC-LED
WOMEN-LED
Top 10 U.S. Biopharma Clusters 2026
Greater Philadelphia Ranked 5th for Biopharmaceutical Development
Greater Philadelphia continues to strengthen its position as one of the nation's premier life sciences hubs, earning the No. 5 ranking in Genetic Engineering News' 2026 list of the Top 10 U.S. Biopharma Clusters.
5thGreater Philadelphia ranked 5th among the nation's top biopharma clusters, climbing two spots.
The annual ranking evaluates regions based on key indicators including NIH funding, venture capital investment, biotechnology patents, laboratory space, and life sciences employment.
Greater Philadelphia made the biggest gain of any region in this year's rankings, climbing two spots to earn the No. 5 position among the nation's top biopharma clusters.
The region maintained its fifth-place ranking for biotechnology patents (17,090 patent families) while rising to fifth in both laboratory space (25.9 million square feet) and NIH funding, securing 3,201 awards totaling $1.94 billion.
Venture capital investment saw especially strong momentum, with the region jumping four spots to fifth after attracting $1.31 billion in 2025 and an additional $616 million in the first quarter of 2026.
U.S. Biopharma Cluster
(up 2 spots)
for Biotechnology
Patents
for Laboratory Space
in NIH Funding
in VC Funding in 2025
for Venture Capital
Investment (up 4 spots)
Rankings and data from Genetic Engineering News' 2026 Top 10 U.S. Biopharma Clusters report.
GO PA Fund
Invests in Lula
The Global Opportunity Pennsylvania Fund II, L.P. (GO PA Fund) invested in Lula, a technology company that aims to transform independent brick-and-mortar convenience stores into last-mile micro-fulfillment centers to deliver a range of need-it-now products to consumers via third-party partners like Doordash and UberEats.
Formed by Ben Franklin Technology Partners of Southeastern Pennsylvania, the GO PA Fund invests in technology-based ventures throughout the commonwealth. The Fund has raised over $34 million in committed capital with the goal of advancing the competitiveness of Pennsylvania’s companies and universities in the global economy.
Anchor Investors
Funding Raised
Investment Opportunities
for Companies
Healthcare
Sector Overview
Healthcare remained the largest sector in Ben Franklin's portfolio in 2025, reflecting the region's strength in life sciences and innovation. From biotechnology and medical devices to digital health solutions, our portfolio companies are advancing technologies that improve patient outcomes, expand access to care, and strengthen Southeastern Pennsylvania's innovation economy.
Leveraged
Active
Portfolio
Companies
Ben Franklin
Invested
Industry
Subsector
Healthcare Portfolio Highlights
Cagent Vascular
cagentvascular.com
Cagent Vascular (Cagent) is an early commercial stage medical device company focused on developing devices for the treatment of cardiovascular disease. The company is selling an angioplasty balloon to treat peripheral artery disease.
InvisALERT
invisalertsolutions.com
InvisALERT has developed a patent-pending technology that delivers patient monitoring compliance and risk management for inpatient healthcare.
Moberg Analytics
moberganalytics.com
Moberg Analytics is helping clinicians make faster, more informed decisions by transforming how complex neurological data is collected, analyzed, and delivered at the bedside. The company’s technology helps hospitals monitor patients with traumatic brain injuries, stroke, coma, cardiac arrest, and other critical neurological conditions, turning overwhelming streams of brain-monitoring data into actionable clinical insights.
Tech
Sector Overview
Technology companies continued to play a vital role in Ben Franklin's portfolio in 2025, driving innovation across software, data & analytics, financial technology, advanced manufacturing, and logistics. By developing solutions that improve efficiency, connectivity, and sustainability, these entrepreneurs are helping businesses adapt to a rapidly changing world while fueling economic growth throughout Southeastern Pennsylvania.
Active
Portfolio
Companies
Ben Franklin
Invested
Leveraged
Industry
Subsector
Tech Portfolio Highlights
Cornelis
cornelisnetworks.com
Cornelis delivers high-performance scale-out and scale-up networking solutions that accelerate AI and HPC workloads. The Cornelis technology enables lossless, congestion-free networking that shortens training time, lowers inference cost and latency, and maximizes compute utilization. From foundation model training and inference to climate modeling and scientific simulation, Cornelis solutions power the most demanding workloads across commercial, academic, government, and cloud environments. With a focus on performance, scalability, and efficiency, Cornelis helps organizations achieve faster insights and greater return on infrastructure investments.
Holganix
holganix.com
Holganix is a soil health company helping farmers restore life to the soil and transform the way food is grown through biological and regenerative solutions.
LoanStar Technologies
loanstartechnologies.com
LoanStar Technologies is a lending firm that provides program consulting, market leading software, and merchant aggregation. LoanStar works with lenders to diversify their consumer loan origination strategies.
